Naruto Shippuden: Gekitou Ninja Taisen EX is the fifth instalment of the Japanese-exclusive Gekitou Ninja Taisen series. This game was also the first Gekitou Ninja Taisen game to be released for the Nintendo Wii as well as the first entry into the EX series.

The game takes place during the Naruto Shippuden series, specifically the first ten episodes of the Kazekage Rescue Mission. The game contains re-done Shippuden versions of 12 characters from the previous games in the series and two new characters specifically from the Shippuden series.

Another notable change to this game is the heavier physics compared to the GameCube titles, and decreased metre gain. As a result, on top of a lower chakra gain when connecting their own attacks, some select attacks now have higher gravity scaling during juggles either horizontally (victims get pushed away further per hit) or vertically, while some don't.

Players can also use the nunchuck to deflect ninja tools and other types of projectiles with proper timing, causing them to return on the exact opposite path of which they flew from. This can be done from any position, save for being knocked down or attacked. Upon deflecting a projectile, despite the laggy animation, the user can instantly followup with an attack.

However, invincibility frames upon landing on the ground from a knockdown have been removed, making on-the-ground hits more easy to achieve than in previous titles.