Fox Sports College Hoops '99 features 120 authentic NCAA teams and their respective logos including all the major conferences at the time and preseason and conference tournaments and updated rosters for that season. It also had the obligatory game modes: Exhibition, Season and Tournament including the ability to skip ahead and compete in the Sweet 16 or the Final Four.

The gameplay is geared towards the style of Courtside with a TV style presentation in association with Fox Sport. It also has three different skill levels along with multiple camera angles and stat tracking throughout an entire season. Classic teams are also available to be played and the ability to customize lineups to their liking. Friends can also go head-to-head in multiplayer mode.