Thirteen years after the original Princess Maker debuted on the MSX with 16-color graphics, GeneX updates the growth-game classic with vibrant visuals and full voice acting for all of the characters in the game. In the game you raise a young girl over an eight year period, until she turns eighteen. To raise your "daughter," you set up her schedule, forcing her to study and attempting to increase her various parameters. You'll also go on vacation and take part in yearly festivals. Over thirty endings await.

When demonic armies rise up and attack the kingdom, more than a few children are rendered orphans. As the hero who beats back the forces of evil and saves the land, one more task is asked of you. Meet Maria, a war orphan who is young and impressionable. For a period of eight years, become a father and raise Maria to become one of thirty possible professions ranging from Queen to warrior to courtesan.

Various tasks and menial jobs may be assigned to Maria to enhance her strength, intelligence, charisma, and many other attributes which affect the path of her growth. For example, if Maria helps with manuscripts, her intelligence rises but her strength withers due to all that learning. A stint as a lumberjack increases her strength but decreases her sex appeal and refinement. Every month, town folk will offer feedback on Maria's progress and comment on her strengths and weaknesses. Items in the game may be purchased and given to Maria to enhance her skills - a dress increases sex appeal but lowers stress while a variety of weapons give her a fighting chance during monster attacks.