Urusei Yatsura: Dear My Friends is a point-and-click adventure game based on the anime and manga of the same name. It is the story of Ataru, a high school lecher who loves nothing more than to try his luck with every pretty girl he meets. Although he is generally good-hearted, he does a good job of hiding that fact.

One day, Earth is beset by alien invaders who will conquer the planet, unless a chosen representative is able to beat an alien representative in their national game: Tag. Incomprehensibly, Ataru is chosen for the task. His opponent is Lum, gorgeous daughter of the invaders' leader. Shinobu, Ataru's long-suffering girlfriend, tells him that she could never marry a loser, and that he had better win the game of Tag if he wants to marry her. Ataru is filled with new hope, and against all odds, he manages to tag the flying Lum.

Ataru is overjoyed that he can now marry Shinobu, but Lum mistakes his victory cry as a marriage proposal. She immediately accepts, and then the two are inseparable - not that Ataru likes it that way. Lum's unconditional love poses no challenge, and Ataru misses the thrill of the chase. Unfortunately, Lum dishes out a massive electric shock every time Ataru so much as breathes in the direction of another girl, so he's stuck!

Urusei Yatsura: Dear My Friends is an original story of their adventures. It features full screen animation, and the original vocal cast of the animated series. The player advances the story by examining and interacting with on-screen objects using a cursor icon.